Large Independent Multi-Center Clinical Trial with Stratum Nutrition’s NEM® Confirms Results in 7 Days

Large Independent Multi-Center Clinical Trial with Stratum Nutrition’s NEM® Confirms Results in 7 Days

Dec 04.2019

December 3, 2019 (Carthage, MO USA) — Stratum Nutrition®, the Global Leader of eggshell and eggshell membrane wellness ingredients, and President, Micah Osborne, announce, “NEM® has become an internationally recognized joint health ingredient as supported in a large, double-blind, placebo-controlled Clinical Trial from Turkey.”

The Journal of Arthritis (J Arthritis 8(4):285.) recently published a large independent multi-center, randomized double-blind, placebo-controlled trial evaluating the efficacy of Stratum’s flagship ingredient, NEM® brand eggshell membrane, in 166 subjects diagnosed with Grade 2 or Grade 3 osteoarthritis of the knee.

This study was conducted at eight different university medical centers in Turkey and confirmed NEM®’s fast results in only 7 days. By Day 30, both knee pain and stiffness had improved by more than 30% in the NEM® -treated subjects. This study also employed a unique blinded, single-crossover design to compare subjects taking NEM® for 90 days versus subjects taking NEM® for 60 days (the former placebo subjects who began taking NEM® after Day 30). A responder analysis found a statistically significant difference between the number of patients having at least a 15% decrease in pain, which was greater in the 90-day NEM® group (71% of subjects) compared to the 60-day NEM® group (53% of subjects).

 

“This is the largest study conducted to date involving NEM® and we are pleased that it was supportive of its fast time to efficacy, even in subjects with moderate to severe arthritis. This, combined with its cartilage protecting effects recently demonstrated in healthy individuals, makes NEM® the perfect adjunctive therapy for those with joint issues,” stated Kevin J. Ruff Ph.D., MBA – Sr. Director of Scientific & Regulatory Affairs for Stratum Nutrition.

Latest Posts

GUTLETE Puts Science-Backed Gut Health in the Spotlight with Bimuno®

GUTLETE Puts Science-Backed Gut Health in the Spotlight with Bimuno®

Oct 23 2026 | Stratum Nutrition
GUTLETE combines Bimuno® with partially hydrolyzed guar gum (PHGG)
From Science to Story: How NEM® Helped Support Gio’s Joint Health.

From Science to Story: How NEM® Helped Support Gio’s Joint Health.

Oct 22 2026 | Stratum Nutrition
After seeing the support NEM® provided as part of Gio’s joint-health routine
Beyond the Hype: When It Comes to Eggshell Membrane, Let the Science Speak

Beyond the Hype: When It Comes to Eggshell Membrane, Let the Science Speak

Oct 15 2026 | Stratum Nutrition
As interest in eggshell membrane collagen continues to grow
footer-logo
LinkedInFacebookInstagramXYoutube
Let's Socialize
Terms of UsePrivacy©2026 Stratum Nutrition, all rights reserved.