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Press Release

ESM and Stratum join Jordan Valley Innovation Center as Corporate Affiliate Member

May 6, 2013 (Carthage, MO USA) - ESM Technologies along with joint venture partner Stratum Nutrition are excited to announce that they are now a corporate affiliate member of the Jordan Valley Innovation Center (JVIC) located in Springfield, Mo. “We are pleased to have ESM Technologies join our list of partners,” stated Allen Kunkel, associate vice president for economic development and director of JVIC. “ESM brings a different set of opportunities for JVIC, and their ties to the region and state are tremendous.”

ESM joins a list of corporate partners that includes: Brewer Science, Crosslink, Lockheed Martin Nanosystems and Mercy R&D . JVIC also works with a number of other local, national and international organizations on a variety of services and research activities.

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Award Winning PREVIDA® Prebiotic Showcases during PFF

April 9, 2013 (St. Charles, MO) Stratum Nutrition, a Novus International Business focusing on nutrition through functional and specialty ingredients, announces that Novus has been awarded the 2012 North American Frost & Sullivan New Product Innovation Award in prebiotics for PREVIDA®. PREVIDA is offered by Stratum Nutrition as an animal health prebiotic ingredient for supporting a healthy gut environment. This is one of many ingredients being showcased during Pet Food Forum in Shamburg, Illinois April 16-17.

Intended for pet food formulations, PREVIDA is a unique prebiotic comprised of an all-natural, AAFCO defined hemicellulose extract that promotes intestinal health for dogs and cats. The product contains a high level of soluble dietary fiber in the form of specific oligosaccharides, which have been shown to provide compelling digestive health benefits. Studies suggest PREVIDA impacts gut microflora and optimizes immune response leading to healthier, more resilient animals.

“PREVIDA is the first holistic digestive health solution for use in pet foods,” said Ingmar Middelbos, Manager, Pet Market for Stratum Nutrition. “Promoting digestive health and overall well-being in pets has been a focus in the industry for years. PREVIDA offers a comprehensive, all-natural digestive health approach.”

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NEM® goes Mass(ive) with Nationwide Jamieson Launch in Walgreens

April 2, 2013 (Carthage, MO USA) ESM Technologies announces a nationwide Walgreens rollout of Advanced Joint Care by Jamieson Laboratories which features NEM® branded eggshell membrane. “We are very proud to be a part of Jamieson’s introduction into the US and to have NEM® associated with a company known for their commitment to quality,” said Micah Osborne, President, ESM Technologies.

Advanced Joint Care with NEM® is part of an important US launch for Jamieson to which Jillian Mariani, Director of Brand Marketing for Jamieson Laboratories says, “NEM has several unique advantages from a consumer perspective – it is a once daily capsule, it can work in as little as 7-10 days, and there is solid science behind it. Additionally, it is sustainably sourced – all in all a very consumer friendly way to support joint health. NEM works well with Jamieson’s values – we aim to provide pure, safe, efficacious, products that are fully traceable from farm to finish, and sustainably.”

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Stratum Nutrition and Pathway International Announce Distribution Agreement

March 14, 2013 (St. Charles, MO USA) Stratum Nutrition announces a distribution arrangement with Pathway International to commercialise and distribute their range of products in Australia and New Zealand.

Pathway International will focus on the specialty, branded supplement ingredient portfolio including: NEM® and ESC® for joint and bone health, ARTINIA® for cardiovascular health, BLIS K12® and BLIS® M18 probiotics for immune and dental health, and ACTAZIN™ NZ kiwi superfruit powder.

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Additional Studies Showcase Benefits of BLIS K12® Probiotic for ENT Health in Children and Adults

Feb 19, 2013 (St. Charles, MO USA) – Stratum Nutrition announces the recent publication of two new studies evaluating BLIS K12® oral probiotic (Streptococcus salivarius K12) and recurrent pharyngitis and/or tonsillitis by S. pyogenes. The independent studies were published in the International Journal of General Medicine and Expert Opinion on Biological Therapy with encouraging findings in both children and adults.

One independent research study evaluated the effectiveness of BLIS K12® oral probiotic for supporting ear and throat health in children(1). Published in the International Journal of General Medicine, an Italian research team demonstrated that they could minimize the reoccurrence of common childhood ear and throat infections, such as otitis media and tonsillitis by around 40% and 90% respectively. Conducted over 10 months, 82 children aged between 4-5 years with a history of recurrent ear and throat infection, were recruited for this study to determine the effect of 90 days of treatment with either the BLIS K12® probiotic or a placebo. Researchers concluded “Prophylactic administration of S. salivarius K12 [BLIS K12®] to children with a history of recurrent oral streptococcal pathology reduced episodes of streptococcal pharyngeal infections and/or tonsillitis as well as episodes of acute otitis media.”

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ARTINIA® Clinical Summary Podcast with Mercodia

Dec 4, 2012 (St. Charles, MO USA) – Stratum Nutrition pharmacology manager, Dr. Joseph L. Evans shares recent published clinical results on ARTINIA® fiber for artery health during podcast interview with Dr. Corinth Auld, Ph.D., Medical Science Liaison for Mercodia. The podcast can be downloaded and heard from the Mercodia Diagnostics website at http://www.mercodia.se/uploads/podcast/EFTR12-02.mp3 .

The clinical trial evaluating ARTINIA®, “Chitin-Glucan Fiber Effects on Oxidized Low-Density Lipoprotein: A Randomized Controlled Trial” was published in the European Journal of Clinical Nutrition in September (2012 Sep 5. doi: 10.1038/ejcn.2012.121). The interview looks at results related to the reduction of oxLDL, a key mediator of atherosclerosis. For more information on the trial, please contact Stratum Nutrition at 800.403.5039.

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BLIS K12® Probiotic Publication of Complete Genome Sequence

November 28, 2012 (St. Charles, MO USA) – Stratum Nutrition announces the recent publication of the complete genome of BLIS K12 (Streptococcus salivarius K12). The study entitled “Genome Sequence of the Lantibiotic Bacteriocin Producer Streptococcus Salivarius Strain K12” was published in the Journal of Bacteriology (2012), 194(21):5959. DOI: 10.1128/JB.01268-12. The sequence data file was deposited in DDBJ/EMBL/GenBank under master record accession number ALIF00000000.

Complete genomic sequencing of BLIS K12 was completed through collaboration with Nestle. Having knowledge of the complete S. salivarius K12 genome significantly contributes to our understanding of the role of this species in the microbial ecology of the mouth and throat and its beneficial role on human health. Dr. Barry Richardson, CEO of BLIS Technologies states, “the completion of the BLIS K12 genome sequence is a significant milestone in the commercial development of the BLIS K12 probiotic and once again confirms the excellent safety of the organism.”

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Stratum Nutrition Celebrates World Egg Day with Egg-ucation

October 10, 2012 (St. Louis, MO) – World Egg Day (WED) is Friday, October 12, and to celebrate, St. Louis local egg farmers and Stratum Nutrition parent company, Novus International, will be talking with students about the nutritional benefits of eating eggs and explaining how eggs get from the farm to their tables. Egg Farmers have a daily commitment to caring for their animals and work hard to provide an all-natural, high-quality protein that helps jump-start any morning breakfast routine.

Eggs are a good source of vitamin D and deliver six grams of high-quality protein to help stay energized throughout the day. Eggs also play a significant role in weight management, muscle strength, healthy pregnancy, brain function, eye health and more. A sustainable use of egg shells and eggshell membrane, Stratum partner ESM Technologies separates the eggshell and membrane to create bone and joint health ingredients. ESC® and NEM®, respectively, are sources of pure calcium and joint supporting nutrients in powder, supplement form.

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ARTINIA® Clinical Trial Results on OxLDL Published in EJCN

September 11, 2012 (St. Louis, MO) Stratum Nutrition, a Novus International Business focusing on nutrition through functional and specialty ingredients, announces the publication of its clinical trial “Chitin-Glucan Fiber Effects on Oxidized Low-Density Lipoprotein: A Randomized Controlled Trial” in the European Journal of Clinical Nutrition (doi:10.1038/ejcn.2012.121).

This gold-standard study design was a 6-week, randomized, double-blind, placebo-controlled clinical trial evaluating the insoluble fiber chitin-glucan (derived from the Aspergillus niger mycelium), commercially available as ARTINIA®. The primary objective of this study was to evaluate the efficacy of chitin-glucan (CG), alone and in combination with a potentially anti-inflammatory olive oil (OO) extract, for reducing oxidized low-density lipoprotein (OxLDL) in subjects with borderline to high LDL cholesterol (LDL-C) levels.

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New Published Data on BLIS K12® Effects on Halitosis

August 29, 2012 (St. Charles, MO USA) – Stratum Nutrition announces the recent independent publication by a Swiss research team at the University of Basel, evaluating BLIS K12 for its ability to inhibit bacteria responsible for the severe bad breath in the oral cavity , known as halitosis. The study entitled “Antimicrobial activity of Streptococcus salivarius K12 on bacteria involved in oral malodour” has been published in the journal Archives of Oral Biology (2012), doi:10.1016/j.archoralbio.2012.02.011.

This study reconfirms an earlier clinical study of 23 subjects by Dr. J. Burton and co-workers, (published in the Journal of Applied Microbiology, v100 (2006) 754–764) where Streptococcus salivarius K12 was shown to be effective at reducing the levels of volatile sulfur compounds (VSC) in the exhaled breath, which are responsible for chronic oral malodor and halitosis.

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